Postdoctoral Position
Two NIH-funded postdoctoral positions are available immediately. Focus of the lab includes:
1. Structure and Function of OTOP proton channels. The goal of these studies is to describe the gating mechanisms and permeation pathway of OTOP channels, combining functional studies (patch-clamp recording) of wildtype and mutant channels with determination of their structure by CryoEM. The candidate will have the opportunity to learn new methods, and conduct cutting-edge research on this understudied family of ion channels.
2. Role of OTOP channels in taste cells and in other physiological contexts. While we continue to explore the role of OTOP1 in taste transduction, we are also interested in expanding our focus to study the contribution of OTOP channels in other tissues and cell types. Towards that end, we have generated mouse strain carrying reporters for OTOP channel expression, or knockouts of OTOP channels. This is an opportunity to explore completely uncharted territory and have a project to take with you to start your own independent lab.
The ideal candidates will have 1-3 years experience with patch-clamp recording and/or experience with biochemistry and molecular biology and a strong record of research accomplishments. The lab is located in the picturesque University Park Campus of the University of Southern California within close driving distance to beaches, mountains and cultural events.
Candidates who are interested in this position should write to liman@usc.edu and include a resume, cover letter, and names of 3 references.
Graduate Students
Positions are available for graduate students interested in either of the projects described above. All graduate students are supported by NIH-funded RAships throughout the duration of their studies.
Liman Lab 